Shiseido Uncovers Skin Softening Anti-wrinkle Mechanism of Pure Retinol

Anti-Aging Medicine
Tags :
Anti-Aging Medicine
Share This :

Shiseido recently described findings that pure retinol (vitamin A)a provides anti-wrinkle efficacy through a new function: skin softening. This effect prevents the progression of wrinkles from the surface of the skin to its deeper layers.

See archived: [interview] Anti-aging for a Modern Market with Tomonobu Ezure, Ph.D., Shiseido

Using its internal and external skin elasticity 3D imaging system,b Shiseido confirmed that the hardening of the stratum corneum increases mechanical stress applied to the dermis when the skin moves with facial expressions, etc. According to the company, this leads to the progression of the gap between the stratum corneum and dermis — the root cause of wrinkles.

A continuous use study was then conducted to evaluate changes in the hardness of the stratum corneum when subjects applied a cream containing pure retinol to one side of the face for 12 weeks. The panel included 35 healthy Japanese women with shallow to slightly deep wrinkles in the outer corner of the eyes.

Results showed the stratum corneum was significantly softer after four weeks of continuous use, compared with baseline. Moreover, with continued use, the softness of the stratum corneum was maintained, with a consequent reduction in the area of wrinkles.

Shiseido emphasized that while pure retinol is highly effective in improving skin, it is easily degraded by oxygen, heat, light, etc. The company used is Retinol TripleLock Technology to stabilize the ingredient and ensure it was delivered to the skin to fully demonstrate effects. 

The company presented the results of this research at the 48th Convention of the Japanese Cosmetic Science Society on Jun. 23, 2023, and parts of this research during the 31st International Federation of Societies of Cosmetic Chemists (IFSCC) Congress 2020, held digitally and in Yokohama.

See archived: Formulating on Trend; Formulating on Trend: Combining Humectants and Retinol

a Per Shiseido, pure vitamin A and not a derivative; reportedly, Shiseido is the only company in Japan approved to blend in pure retinol (vitamin A) as a quasi-drug active ingredient

b Patented technology jointly developed by Shiseido, Honda Electronics Co., Ltd., and Toyohashi University of Technology; the technology converts the reflected ultrasonic signals from the inside of the skin into the modulus of elasticity

Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

Popular News Posts


Our Exclusive Products

Our Store

Our mission is simple, offer quality products that make our customers lives better at a reasonable price, while ensuring a hassle-free shopping experience. This means that before we bring a product to market, we test it to ensure that it meets our high-level quality standards. Our customer service team understand our products and can answer most every product related question quickly and efficiently. We strive everyday to meet and exceed our customers’ expectations of quality and support! Should we ever fail to meet this expectation – contact us and we will make it right!

Our Value: We are proud of our product and accomplishments, but we typically don’t shout it from the rooftop. Instead, we prefer to let our product and customers do the talking. Our core values can be recognized in our product. The qualities we strive for include:

Pragmatism: We design simple, useful solutions for common needs
Quality: From design to final product, we strive for durable solutions that work
Originality: Creativity and innovation are what makes our product unique
Design: Our minimalist and bold design language focuses on functionality and simplicity that is timeless

0 +

Top Rated Products

0 +

Happy Customers