Experts discuss improving enrollment in acute stroke trials

Health News
Tags :
Health News
Share This :

Credit: CC0 Public Domain

Clinical trials are a critical step in improving treatments and care for acute stroke patients, and enrolling a large and diverse patient population in trials helps push research forward.

At the Stroke Treatment Academic Industry Roundtable XII meeting in March, stroke physicians, researchers, industry representatives and members of the National Institute of Neurological disorders and Stroke and the U.S. Food and Drug Administration discussed the current status of enrolling patients in acute stroke trials and the most pressing issues impacting enrollment.

The meeting’s review and recommendations were recently published in the journal Stroke, led by corresponding author Joseph Broderick, MD, professor in the University of Cincinnati’s Department of Neurology and Rehabilitation Medicine in the College of Medicine, director of the UC Gardner Neuroscience Institute and a UC Health physician.

Meeting members discussed enrollment issues including:

  • The need for emergency consent in the U.S. and other countries due to the time-sensitive nature of treatments being tested for acute stroke patients
  • Designing patient eligibility criteria in order to maximize both overall enrollment numbers and a diverse and representative patient sample that represents the broader population
  • Investigator, study coordinator and pharmacist’s availability outside of business hours
  • Delays in sites opening trials due to contractual and other issues

“In conclusion, enrollment of participants is the lifeblood of acute stroke trials and is the rate-limiting step for testing an exciting array of new approaches to improve patient outcomes,” Broderick and his colleagues wrote. “In particular, efforts should be undertaken to broaden the medical community’s understanding and implementation of emergency consent procedures and to adopt designs and processes that are easily incorporated into standard workflow and that improve trials’ efficiencies and execution.

“Research and actions to improve enrollment in ongoing and future trials will improve stroke outcomes more broadly than any single therapy under consideration,” the authors continued.

More information:
Joseph P. Broderick et al, Enhancing Enrollment in Acute Stroke Trials: Current State and Consensus Recommendations, Stroke (2023). DOI: 10.1161/STROKEAHA.123.044149

Experts discuss improving enrollment in acute stroke trials (2023, September 14)
retrieved 15 September 2023

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

Popular News Posts


Our Exclusive Products

Our Store

Our mission is simple, offer quality products that make our customers lives better at a reasonable price, while ensuring a hassle-free shopping experience. This means that before we bring a product to market, we test it to ensure that it meets our high-level quality standards. Our customer service team understand our products and can answer most every product related question quickly and efficiently. We strive everyday to meet and exceed our customers’ expectations of quality and support! Should we ever fail to meet this expectation – contact us and we will make it right!

Our Value: We are proud of our product and accomplishments, but we typically don’t shout it from the rooftop. Instead, we prefer to let our product and customers do the talking. Our core values can be recognized in our product. The qualities we strive for include:

Pragmatism: We design simple, useful solutions for common needs
Quality: From design to final product, we strive for durable solutions that work
Originality: Creativity and innovation are what makes our product unique
Design: Our minimalist and bold design language focuses on functionality and simplicity that is timeless

0 +

Top Rated Products

0 +

Happy Customers