Multi-omics assist in designing the next generation of COVID-19 therapeutics and vaccines

Health News
Tags :
Health News
Share This :


Multi-omics in COVID-19, assist in designing the next generation of therapeutics and vaccines
Multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, epigenomics and metallomics, have helped uncover the molecular processes underlying SARS-Cov-2 and understand the host responses to virus and vaccine. The emerging multi-omic technologies assist in designing the next generation of powerful therapeutics and vaccines. Credit: Science China Press

The ongoing COVID-19 pandemic has raised global concern on public health. There are major challenges ahead to develop new therapeutics and vaccines for difficult-to-target pathogens, for which we urgently need a better understanding of protective immunity. The development of high-throughput sequencing, mass spectrometry, computer science and algorithms provide us with a comprehensive and systematic picture of life processes, and enhance our understanding of human immunity and diseases.

In a new study published in the journal National Science Review, researchers present an up-to-date overview of the latest applications of multi-omics technologies in strategies addressing COVID-19. Firstly, they discuss how emerging multi-omics technologies—including genomics, transcriptomics, proteomics, metabolomics, epigenomics and metallomics—have helped create an understanding of the structural and molecular features of the virus.

Then, they elaborate on how multi-omics technologies have played a key role in assisting the screening of antiviral drugs, the characterization of drug antiviral activities, and the study of the mechanism of action of antiviral drugs. In addition, many multi-omics approaches, including glycomics, transcriptomics, proteomics and others provide potential value in finding the characteristics of pathogens and elucidating host responses to vaccines, which can ultimately lead to a roadmap for vaccine design.

This review aims to provide suggestions towards the development of highly effective therapeutics (antibodies and small molecular drugs) and vaccines, which is particularly important in chemistry, material and immunology science.

This study was led by Dr. Chunying Chen (National Center for Nanoscience and Technology), Dr. Yechun Xu (Shanghai Institute of Materia Medica, Chinese Academy of Sciences), Dr. Chengqi Yi (Peking University) and Dr. Guanbo Wang (Peking University).

More information:
Mengyu Guo et al, Multi-omics in COVID-19: Driving development of therapeutics and vaccines, National Science Review (2023). DOI: 10.1093/nsr/nwad161

Citation:
Multi-omics assist in designing the next generation of COVID-19 therapeutics and vaccines (2023, July 25)
retrieved 26 July 2023
from https://medicalxpress.com/news/2023-07-multi-omics-generation-covid-therapeutics-vaccines.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.





Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

Popular News Posts

Categories

Our Exclusive Products

Our Store

Our mission is simple, offer quality products that make our customers lives better at a reasonable price, while ensuring a hassle-free shopping experience. This means that before we bring a product to market, we test it to ensure that it meets our high-level quality standards. Our customer service team understand our products and can answer most every product related question quickly and efficiently. We strive everyday to meet and exceed our customers’ expectations of quality and support! Should we ever fail to meet this expectation – contact us and we will make it right!

Our Value: We are proud of our product and accomplishments, but we typically don’t shout it from the rooftop. Instead, we prefer to let our product and customers do the talking. Our core values can be recognized in our product. The qualities we strive for include:

Pragmatism: We design simple, useful solutions for common needs
Quality: From design to final product, we strive for durable solutions that work
Originality: Creativity and innovation are what makes our product unique
Design: Our minimalist and bold design language focuses on functionality and simplicity that is timeless

0 +

Top Rated Products

0 +

Happy Customers